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早在1900年Landsteiner 首先证实人类红细胞的ABO 血型系统,使输血成为可能并奠定基础。半个多世纪后,人们相继发现各种血液成份均具有型别差异。有关白细胞血型至50年代方被认识,现已发现各形态白细胞的抗原决定簇不尽相同,对其中淋巴细胞和粒细胞抗原认识较清。由抗原所致同种免疫性抗体,对器官移植的成败及产生输血发热反应密切相关。本文就白细胞抗体检测与输血间的关系作一简述。
As early as 1900, Landsteiner first confirmed the human erythrocyte ABO blood group system, making blood transfusion possible and laying a foundation. More than half a century later, people have found a variety of blood components have type differences. About 50 years of leucocyte blood type is recognized, has now been found that the morphological leukocyte antigenic determinants are not the same, of which lymphocytes and granulocyte antigen awareness more clearly. Antigenic antibodies caused by alloimmune, the success of organ transplantation and transfusion fever is closely related. This article briefly reviews the relationship between leukocyte antibody testing and blood transfusion.