心肌缺血再灌注损伤机制是近年研究的热点之一 ,病因复杂 ,与多种因素有关 ,其中炎症反应与再灌注损伤关系密切。白细胞、血小板及内皮细胞粘附分子在炎症病理过程中有重要作用。因而粘附分子在再灌注损伤中的机制对进一步阐明心肌再灌注损伤的病理生理过程及对临床提供治疗上的理论依据具有实际意义 Myocardial ischemia-reperfusion injury mechanism is one of the hot spots in recent years, the etiology is complex, and a variety of factors, including inflammation and reperfusion injury are closely related. Leukocytes, platelets and endothelial cell adhesion molecules play an important role in the pathological process of inflammation. Therefore, the mechanism of adhesion molecules in reperfusion injury is of practical significance to further elucidate the pathophysiological process of myocardial reperfusion injury and provide a theoretical basis for the treatment of clinical