目的了解宁夏地区职业人群高尿酸血症的流行特征及相关危险因素,为防治高尿酸血症提供参考。方法运用整群随机抽样的方法,选取2007年1月-2009年12月至宁夏医科大学附属医院进行健康检查的宁夏地区政府机关及国有集体所有制事业单位的职工作为调查对象,进行问卷调查、健康检查及实验室检测。结果共调查5 545人,资料齐全者为5 415人,宁夏地区职业人群高尿酸血症总患病率为16.8%,其中男性患病率为22.2%,女性病率为8.2%,男性患病率明显高于女性(χ2=166.574,P<0.01);高尿酸血症组的肥胖、高血压、高血糖、高甘油三酯、高总胆固醇、低高密度脂蛋白-C和高低密度脂蛋白-C的患病率均高于正常对照组,差异均有统计学意义(P<0.01)。结论与国内同期流行病学调查结果相比较,宁夏部分人群高尿酸血症患病率处于较高水平,男性明显高于女性。 Objective To understand the prevalence and risk factors of hyperuricemia among occupational population in Ningxia and to provide reference for the prevention and treatment of hyperuricemia. Methods A cluster random sampling method was used to select the employees of Ningxia government agencies and state-owned collective-owned enterprises in Ningxia Medical University Affiliated Hospital from January 2007 to December 2009 as the survey subjects, to conduct questionnaire survey, health survey Inspection and laboratory testing. Results A total of 5 545 people were surveyed, with 5 415 informants. The total prevalence of hyperuricemia was 16.8% in the occupational population in Ningxia, including 22.2% for males and 8.2% for females The rates of obesity, hypertension, hyperglycemia, hypertriglyceridemia, high total cholesterol, low-density lipoprotein-C and high and low density lipoprotein in hyperuricemia group were significantly higher than those in female group (χ2 = 166.574, P <0.01) The prevalence of protein-C was higher than that of the normal control group, the difference was statistically significant (P <0.01). Conclusions Compared with the epidemiological findings of the same period in China, the prevalence of hyperuricemia in some people in Ningxia is at a high level, which is significantly higher in males than in females.