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目的:了解A群轮状病毒引起婴幼儿腹泻的感染情况,为临床诊疗提供参考。方法:采集腹泻婴幼儿的新鲜粪便标本,采用A群轮状病毒诊断试剂盒,对绍兴市妇幼保健院2009年2月至2010年1月儿科门诊603例腹泻婴幼儿的粪便标本进行A群轮状病毒的检测。结果:603例腹泻婴幼儿中检出160例A群轮状病毒阳性标本,阳性率26.5%。各个年龄段的感染率分别为:3～6个月组为10.3%,6个月至1岁组为38.1%,1～2岁组为26.0%,2～5岁组为35.7%,经χ2检验,P<0.01。以6个月至1岁组为A群轮状病毒的高发年龄段。男性患儿感染率为31.0%,女性患儿感染率为19.6%,经χ2检验,P<0.05,男性患儿感染A群轮状病毒较多见。A群轮状病毒引起的婴幼儿腹泻以11～1月为高发感染期,感染率分别为23.1%、51.4%、37.3%。结论:6个月至1岁组A群轮状病毒感染较多见,11～1月为感染高峰期,应重视腹泻病原的检测,以明确诊断,防止滥用抗菌药物而导致肠道菌群失调,发生二重感染。
Objective: To understand the infection caused by rotavirus A in infants and young children and to provide references for clinical diagnosis and treatment. Methods: Fresh stool samples of diarrhea infants and young children were collected. A group A rotavirus diagnostic kit was used to test the stool samples of 603 diarrhea infants in pediatric outpatient department of Shaoxing MCH from February 2009 to January 2010. Virus-like test. Results: A total of 160 rotavirus A positive samples were detected in 603 diarrhea infants. The positive rate was 26.5%. The infection rates in all age groups were 10.3% in 3-6 months, 38.1% in 6 months to 1 year old, 26.0% in 1-2 years old and 35.7% in 2-5 years old, Test, P <0.01. A group of rotavirus high-incidence age of 6 months to 1 year old group. The infection rate of males was 31.0%, and the infection rate of females was 19.6%. By χ2 test, P <0.05, males infected with group A rotavirus were more common. A group of rotavirus-induced infantile diarrhea in 11 to January for the high incidence of infection, the infection rates were 23.1%, 51.4%, 37.3%. Conclusion: A group of rotavirus infection from 6 months to 1 year old group is more common, from January to January is the peak of infection, should pay attention to the detection of diarrhea pathogens in order to confirm the diagnosis, prevent the abuse of antibiotics and lead to intestinal flora , Double infection occurred.