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已知动脉粥样硬化是大多数心肌梗塞和脑梗塞的致病原因,尽管文献对它的记述已有百余年,但对其病因的认识只是近10年的事。由于开展血液和动脉壁细胞生物学作用的研究,使我们对动脉粥样硬化病因学的认识发生了一系列的变化;而且实验病理学和细胞、分子生物学的发展,为进一步阐述致动脉硬化假说提供了可能。这一发展的结果,使在病变的早期即能发现处于致动脉硬化高危险状态的人。
Atherosclerosis is known to be responsible for most of the causes of myocardial infarction and cerebral infarction. Although it has been documented in the literature for more than a century, the understanding of its etiology has been only 10 years. Because of the blood and arterial wall cell biology research, so that our understanding of atherosclerosis etiology has undergone a series of changes; and experimental pathology and cell, molecular biology, in order to further elaborate atherosclerosis Hypothesis offers the possibility. As a result of this development, early stage lesions can be found in people at high risk of atherosclerosis.