目的了解西昌市邛海周边地区地形、地貌、疫水来源、感染性钉螺分布等因素与居民血吸虫病感染之间的关系。方法根据全球卫星定位系统 ( GPS)测绘图及钉螺调查结果 ,在西昌市邛海周边 4个乡 ,选择 1 96个点进行疫水测定。小鼠每日上下午各接触疫水 1 h,连续 5 d共 1 0 h,饲养 35 d后解剖 ,了解感染情况。结果人群平均感染率与测定点阳性率间存在正相关 ( 0 .0 5 >P>0 .0 2 ) ,阳性点的分布在地理特征上也呈现出一定的规律性。居民区疫水测定点阳性率与人群感染率相符 ,感染程度越重的村受外来水源的影响越大 ,汇水地形感染点感染率极高。在人群感染率较低的村 ,疫水测定结果与阳性钉螺水系分布符合率都高 ;而在人群感染率高的地区 ,则出现疫水测定阳性点与发现阳性钉螺水系感染点符合率极高而疫水测定阴性点与未发现阳性钉螺水系感染点符合率极低的情况。结论疫水测定结果表明 ,在梯地、阶地所占面积大的村 ,哨鼠感染率高 ,人群感染率也高 ;平地所占面积大的村 ,哨鼠感染阳性率低 ,人群感染率也低。在开展血吸虫病防治时应重视外来水源的影响 ,扩大防治范围 ,也应重视居民区附近的血吸虫病防治 ,在高感染地区必须在钉螺调查的基础上结合疫水测定结果才能更为准确地判断该地区水体污染程度 Objective To understand the relationship between the factors such as topography, topography, source of infectious water and the distribution of infectious snails in Xichang City and the infection of schistosomiasis. Methods According to the global satellite positioning system (GPS) mapping and snail survey results, we selected 1 96 points in 4 townships around Qionghai in Xichang for water quality measurement. The mice were exposed to water for 1 h each morning and afternoon for 5 consecutive days for 10 h. After 35 d of feeding, the mice were dissected to understand the infection. Results There was a positive correlation between the average infection rate of the population and the positive rate of the measurement point (0. 05> P> 0. 0 2). The distribution of the positive point also showed some regularity on the geographical characteristics. The positive rate of epidemic water determination point in residential areas is consistent with the population infection rate. The more affected villages are affected by external water sources, and the infection rate at the site of catchment topography is extremely high. In the villages with low population infection rate, the coincidence rates of the measured results of water and the positive snail water system were all high. In the areas with high population infection rate, the positive points of the water samples were found and the positive rates of the found sites of the positive snail water systems were very high However, there was a very low coincidence rate between the negative point of water inoculation and the point of non-positive snail water infection. Conclusions The results of the epidemic water test showed that in the villages and terraces where the terraces and terraces occupy a large area, the infection rate of the sentinel mice is high, and the infection rate of the population is also high. The positive rate of infected villages and sentinels is relatively low in the area occupied by the plains, low. In the prevention and treatment of schistosomiasis should pay attention to the impact of external water sources to expand the scope of prevention and control, but also should pay attention to the prevention and treatment of schistosomiasis near residential areas in high-infected areas must be based on snail surveys combined with the results of the determination of water can be more accurately determine The extent of water pollution in the area