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目的 应用彩色多普勒测定肝癌患者介入治疗 (TAE)术前后血流指数的改变 ,为评估术后疗效及预后提供依据。方法 对 58例原发性肝癌患者使用彩色多普勒超声 ,于介入治疗术前 5～ 7天及术后 7～ 1 0天、6个月和 1 2个月测定病灶内彩色动脉型血流的最大流速 (PSV)及阻力指数 (RI)。结果 TAE后肿瘤内径缩小 ,PSV下降 ,RI增高 ,但生存期 <1年组栓塞后 6月PSV、RI改变并不显著 ,与生存期>1年组相比有显著差异 (P <0 .0 1 )。结论 原发性肝癌患者在介入治疗后 ,癌肿内血流动力学发生不同程度变化 ,是评估预后的重要因素。
Objective To evaluate the change of blood flow index before and after interventional therapy (TAE) in patients with liver cancer by color Doppler echocardiography, and to provide evidence for the evaluation of postoperative efficacy and prognosis. Methods Fifty-eight patients with primary liver cancer were examined by color Doppler ultrasonography. Intra-arterial color flow in the lesion was measured at 5 to 7 days before operation and at 7 to 10 days, 6 months and 12 months after operation. The maximum flow rate (PSV) and resistance index (RI). Results After TAE, the tumor diameter decreased, PSV decreased and RI increased. However, the changes of PSV and RI in the group with less than 1 year of survival after the embolization were not significant (P <0. 0) 1 ). Conclusion Hemodynamics in cancer patients with varying degrees of change after interventional therapy is an important factor to evaluate prognosis in patients with primary liver cancer.