论文部分内容阅读
目的探讨电视胸腔镜胸腺扩大切除手术治疗胸腺瘤合并重症肌无力的应用价值。方法 2014年3月—2015年6月选择本院治疗的98例胸腺瘤合并重症肌无力患者作为研究对象,采取随机数字表法分为观察组和对照组各49例,对照组给予开胸手术治疗,观察组给予电视胸腔镜胸腺扩大切除手术治疗,记录两组患者的治疗效果。计量资料比较采用t检验,计数资料比较采用χ2检验,P<0.05为差异有统计学意义。结果观察组患者手术时间、胸腔引流时间、住院时间[(102.85±8.97)min、(2.32±1.14)、(6.28±1.34)d]显著短于对照组[(119.83±14.72)min、(3.97±1.86)、(8.97±2.86)d],差异均有统计学意义(均P<0.05);观察组患者术中出血量为(78.54±10.77)ml,显著少于对照组的(154.72±24.56)ml,差异有统计学意义(P<0.05)。对照组患者并发症发生率为16.33%(8/49),观察组为4.08%(2/49),比较差异有统计学意义(χ2=4.009,P<0.05)。观察组患者躯体功能、角色功能、认知功能、情绪功能、社会功能评分及总分[(88.12±4.87)、(69.88±6.82)、(79.67±5.87)、(84.51±6.32)、(84.11±4.89)、(80.57±7.65)分]显著高于对照组[(78.91±2.33)、(60.03±3.47)、(70.04±2.89)、(75.31±4.17)、(78.86±3.18)、(72.15±3.44)分],差异均有统计学意义(均P<0.05)。结论电视胸腔镜胸腺扩大切除手术治疗胸腺瘤合并重症肌无力效果可靠,缩短手术时间、胸腔引流和住院时间,提升患者术后生活质量,值得在临床大力推广使用。
Objective To investigate the value of thoracoscopic thoracoscopic surgery for thymoma combined with myasthenia gravis. Methods From March 2014 to June 2015, 98 patients with myasthenia gravis combined with myasthenia gravis treated in our hospital were enrolled in this study. The random number table was divided into observation group (49 cases) and control group (49 cases). The control group was given thoracotomy The treatment group and the observation group were given thoracoscopic thymus enlargement and excision surgery, and the treatment effect was recorded in both groups. Measurement data were compared using t test, count data were compared using χ2 test, P <0.05 for the difference was statistically significant. Results The operation time, chest drainage time and hospital stay in the observation group [(102.85 ± 8.97) min, (2.32 ± 1.14) and (6.28 ± 1.34) d] were significantly shorter than those in the control group [(119.83 ± 14.72) min and (3.97 ± 1.86 and 8.97 ± 2.86, respectively] (all P <0.05). The bleeding volume in the observation group was (78.54 ± 10.77) ml, which was significantly lower than that in the control group (154.72 ± 24.56) ml, the difference was statistically significant (P <0.05). The incidence of complications in the control group was 16.33% (8/49) in the observation group and 4.08% (2/49) in the observation group. The difference was statistically significant (χ2 = 4.009, P <0.05). The body function, role function, cognitive function, emotional function, social function score and total score [(88.12 ± 4.87), (69.88 ± 6.82), (79.67 ± 5.87), (84.51 ± 6.32) and (84.11 ± (78.91 ± 2.33), (60.03 ± 3.47), (70.04 ± 2.89), (75.31 ± 4.17), (78.86 ± 3.18), (72.15 ± 3.44), (80.57 ± 7.65) ) Points], the differences were statistically significant (all P <0.05). Conclusions Video-assisted thoracoscopic thymus resection of thymoma with myasthenia gravis has the advantages of reliable operation, shortened operation time, chest drainage and hospitalization, and improved postoperative quality of life. It is worth to be promoted in clinical practice.