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目的：分析标准大骨瓣开颅治疗重度颅脑损伤合并脑疝的临床效果及注意事项。方法分析我院神经外科收治的重度颅脑损伤出现脑疝患者360例的临床资料，均采用标准大骨瓣开颅治疗。结果标准大骨瓣开颅治疗重度颅脑损伤患者后神经功能和肢体运动功能均好于治疗前，P<0.05，差异均有统计学意义。结论标准大骨瓣开颅治疗重度颅脑损伤合并脑疝的效果明显，神经功能及肢体运动功能明显改善。但手术方法应该遵循个体化的原则，不能随便应用这种损伤大的手术方式。“,”Objective To investigate the clinical ef ect and cautions of standard large trauma craniotomy for severe craniocerebral injury complicated with cerebral hernia. Method:Observation on the clinical data of 360 cases of severe craniocerebral injury complicated with cerebral hernia, which were treated with standard large trauma craniotomy in our hospital. Results The patients of severe craniocerebral injury accepted standard large trauma craniotomy can have bet er nerve function and limb motor function than preoperation, P<0.05, which shows significant dif erence. Conclusion The standard large trauma craniotomy for severe craniocerebral injury complicated with cerebral hernia presented obvious treatment ef ect. Both nerve function and limb motor function can significantly improved. However, this operation method should fol ow the principle of individualization.