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目的探讨神经节苷酯在临床治疗早产儿颅内出血(ICH)的疗效分析。方法经头颅B超确诊为颅内出血的早产儿76例进行回顾性分析,随机分成观察组与治疗组,每组38例。观察组采用常规的综合治疗,治疗组在常规治疗的基础上,加予神经节苷酯20 mg/d静脉滴注,1次/d,10~40 d为1疗程。观察两组患儿的疗效对比。结果治疗组在治疗总有效率和NBNA评分方面均优于观察组,两组患儿差异具有统计学有意义(P<0.05)。结论神经节苷酯治疗早产儿颅内出血有较好临床疗效,可以降低患儿产生神经系统疾病的发生率,值得在临床推广。
Objective To investigate the efficacy of ganglioside in the treatment of intracranial hemorrhage (ICH) in premature infants. Methods Totally 76 preterm infants with intracranial hemorrhage diagnosed by skull B ultrasound were retrospectively analyzed and randomly divided into observation group and treatment group with 38 cases in each group. The observation group were treated with conventional comprehensive treatment. The treatment group received intravenous infusion of 20 mg / day of ganglioside once a day for 10 to 40 days on the basis of routine treatment. Observed the efficacy of two groups of children compared. Results The treatment group was better than the observation group in terms of total effective rate and NBNA score, the difference between the two groups was statistically significant (P <0.05). Conclusion Ganglioside treatment of intracranial hemorrhage in preterm children have better clinical efficacy, can reduce the incidence of neurological diseases in children, it is worth in the clinical promotion.