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目的探讨血小板活化因子(CD62P)与类风湿性关节炎(RA)及其活动性的关系。方法比较RA活动组、缓解组和正常对照组CD62P表达阳性率的变化。结果RA活动组CD62P表达阳性率比RA缓解组和正常照组均显著增高(P<0.05)。结论RA患者CD62P表达增高与疾病活动有关;CD62P高表达可能是RA患者好发心血管疾病的原因之一。
Objective To investigate the relationship between platelet-activating factor (CD62P) and rheumatoid arthritis (RA) and its activity. Methods The changes of the positive rate of CD62P in RA active group, remission group and normal control group were compared. Results The positive rate of CD62P expression in RA activity group was significantly higher than that in RA remission group and normal control group (P <0.05). Conclusion The increased expression of CD62P in RA patients is related to the disease activity. The high expression of CD62P may be one of the causes of cardiovascular disease in RA patients.