李约瑟和鲁桂珍在1968年著文认为我国宋代记载的阳炼秋石是世界上最早提炼性激素的方法。此后有不少研究者附合这种说法。最近台湾学者刘广定连续发表文章对李约瑟的说法提出异议。其论点如下:1.《水云录》或《苏沈良方》中用十余石尿作原料,如果是成人的尿,则约含性激素20克。性激素中只有 Needham and Lu Guizhen wrote in 1968 that Yang Lian Qiushi recorded in the Song Dynasty in China was the earliest method of extracting sex hormones in the world. Since then, many researchers have attached this view. Recently Taiwan scholar Liu Guangding published an article on Needham’s assertion. The arguments are as follows: 1. “Shui Yun Lu” or “Ssangliangfang” with more than ten stone as raw materials, if it is adult urine, about sex hormone 20 grams. Sex hormones only