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目的研究肌注缩宫素联合口服卡孕栓对预防产后出血的应用价值。方法选取2012年5月—2014年5月在该院分娩的210例足月妊娠产妇为研究对象,采用随机分组的方式,将210例产妇分为三组,分别为A组、B组和C组,每组各70例。A组产妇在胎儿娩出后,给予肌肉注射缩宫素。B组产妇在胎儿娩出后,给予舌下含服卡孕栓。C组产妇在胎儿娩出后,给予肌注缩宫素联合舌下含服卡孕栓,观察三组产妇产后2h和24h的出血量和出血率。结果三组产妇第三产程时间、产后2h出血量和产后24h出血量相比,C组要明显少于A组和B组,差异有统计学意义(F=18.683,42.969,105.192;P均<0.05)。三组产后出血率相比,C组明显低于A组和B组,差异有统计学意义(χ~2=7.500,P<0.05)。三组产妇的不良反应总发生率相比,差异无统计学意义(χ~2=0.615,P>0.05)。结论肌注缩宫素联合口服卡孕栓能有效预防产后出血,两者之间的协调作用良好,是一种安全、可靠、简便的方法,值得在临床上进行应用和推广。
Objective To study the value of intramuscular oxytocin combined with oral carbapethrin in preventing postpartum hemorrhage. Methods A total of 210 full-term pregnant women delivered in our hospital from May 2012 to May 2014 were selected as study subjects. 210 pregnant women were randomly divided into three groups: group A, group B and group C Group, each group of 70 cases. A group of mothers after the baby was delivered, given intramuscular oxytocin injection. B group of mothers after the baby was delivered sublingual buccal tablets. Group C maternal fetus after delivery, intramuscular injection of oxytocin combined with sublingual carboplatin, observe the three groups of maternal postpartum 2h and 24h of bleeding and bleeding rate. Results Compared with group A and group B, the time of the third stage of labor, the amount of hemorrhage 2 h postpartum and the amount of hemorrhage 24 h postpartum were significantly lower in group C than those in group A and group B (F = 18.683, 42.969, 105.192, P < 0.05). The postpartum hemorrhage rates in three groups were significantly lower than those in groups A and B (χ ~ 2 = 7.500, P <0.05). There was no significant difference in the total incidence of adverse reactions between the three groups (χ ~ 2 = 0.615, P> 0.05). Conclusion Intramuscular injection of oxytocin combined with oral carbamazepine can effectively prevent postpartum hemorrhage, and the coordination between them is good, which is a safe, reliable and simple method that is worthy of clinical application and promotion.