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28名病人随机分为二组,其中11名病人接受短期治疗,17名病人接受长达8周的长期治疗,短期组一次口服10mg硝苯吡啶;长期组剂量力30mg/日。根据高血压严重性指数(severity-indcx)将病人分为二类。严重性指数小于4者为轻度高血压;大于10者为重度高血压。试验结果:短期组,轻度高血压病人血压降低的数值均低于治疗前血压的20%:重度高血压病人血压降低幅度较大,其降低值均高于20%。重度高血压病人收缩压的降低值与治疗前血压有明显的相关性(γ=-0.72,P<0.05)长期组,所有病人血压均显著下降,但血压下降的幅度仍与治疗前的血压有关,即治疗前血压越高。下降的幅度越大
Twenty-eight patients were randomized into two groups: 11 patients received short-term treatment, 17 patients received long-term treatment of up to 8 weeks, and 10 mg of nifedipine were given orally once as the short-term group. The long-term dose of 30 mg / day was used. Patients were divided into two categories based on severity-indcx. Severe index of less than 4 were mild hypertension; more than 10 were severe hypertension. Test results: The short-term group, patients with mild hypertension lower blood pressure values were lower than 20% of pre-treatment blood pressure: severe hypertension decreased blood pressure greater, the decrease was higher than 20%. The systolic blood pressure in patients with severe hypertension was significantly correlated with the pre-treatment blood pressure (γ = -0.72, P <0.05). In the long-term group, all patients’ blood pressure decreased significantly, but the decline of blood pressure was still related to the blood pressure before treatment , That is, the higher the blood pressure before treatment. The greater the decline