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目的探讨结节性甲状腺肿(NG)合并甲状腺癌(TC)的诊断和治疗方法。方法回顾性分析自2007年以来我院收治的结节性甲状腺肿患者的临床资料,探讨结节性甲状腺肿和甲状腺癌并存的临床特点、诊断和治疗方法。结果同期手术治疗结节性甲状腺肿患者307例,其中并发甲状腺癌38例(12.4%),包含乳头状癌21例(55.3%),滤泡状癌12例(31.6%),髓样癌5例(13.1%)。所有患者均手术治疗,行术中快速冷冻切片病理检查,并根据检查结果采取不同的手术方式。结论结节性甲状腺肿患甲状腺癌的概率较高,怀疑甲状腺癌者应进行穿刺活检和术中快速切片病理检查,可提高确诊率。根据快速冷冻切片检查结果进行手术以及术后服用甲状腺素治疗有利于降低复发和死亡。
Objective To investigate the diagnosis and treatment of nodular goiter (NG) combined with thyroid cancer (TC). Methods The clinical data of patients with nodular goiter admitted in our hospital from 2007 to 2007 were analyzed retrospectively to investigate the clinical features, diagnosis and treatment of nodular goiter and thyroid cancer. Results There were 307 patients with nodular goiter during the same period, of which 38 (12.4%) had concurrent thyroid cancer, including 21 papillary carcinoma (55.3%), follicular carcinoma 12 (31.6%), medullary carcinoma 5 Example (13.1%). All patients were surgically treated, intraoperative rapid frozen section biopsy, and according to the test results to take a different surgical approach. Conclusions Nodular goiter has a high probability of thyroid cancer. Thyroid cancer patients should have biopsy and intraoperative rapid biopsy to improve the diagnosis rate. Surgery based on rapid frozen biopsy results and postoperative thyroxine treatment are helpful in reducing relapse and death.