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巨大泌乳素瘤的治疗选择仍然是一个有争议的问题。神经外科医生倾向于主张,泌乳素瘤的药物治疗必须长期连续给药。然而在多巴胺能药物治疗几年后,虽然药物剂量大大减少,但巨大泌乳素瘤也不再扩展。尚无长期(5~10年)治疗后撤药的研究。经蝶部手术治疗巨大泌乳素瘤也仅有极少数
The choice of treatment for macroprolactinoma remains a controversial issue. Neurosurgeons tend to claim that prolactin therapy must be administered continuously for long periods. However, after a few years of dopaminergic therapy, the huge prolactinoma no longer expands despite the dramatic reduction in drug dose. There is no long-term (5 to 10 years) withdrawal study after treatment. Transsphenoidal surgical treatment of macroprolactinoma is also rare