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目的:对不同给药方式的盐酸氨溴索治疗儿童呼吸系统疾病患者的治疗效果进行观察对比,得出更有效的给药方式。方法:统计该院于2013年2月至2015年3月收治的儿童呼吸系统疾病患者共计92例。将所有患儿平均随机分为两组,对照组给予静脉注射药物治疗、观察组患者行氧气驱动雾化治疗。对比两组患儿的疾病康复情况,得出治疗效果。结果:对照组46例患儿的临床症状平均好转时间为(3.82±0.22)d、平均氧疗时间为(2.08±0.33)d、患儿平均住院时间为(10.39±1.73)d,治疗效果显效11例、有效22例、无效13例,总有效率为71.74%。观察组46例患儿的临床症状平均好转时间为(2.52±0.35)d、平均氧疗时间为(1.32±0.23)d、患儿平均住院时间为(7.64±1.19)d,治疗效果显效17例、有效26例、无效3例,总有效率为93.48%。两组患儿平均的临床症状好转时间、氧疗时间、住院时间和总有效率之间数值对比,(P值均<0.05),差异具有统计学意义。结论:对儿童呼吸系统疾病患者的治疗,采用盐酸氨溴索行雾化治疗方式的综合效果要明显优于注射治疗。值得临床推广应用。
OBJECTIVE: To observe and compare the therapeutic effect of Ambroxol Hydrochloride for children with respiratory diseases in different modes of administration, and to find a more effective mode of administration. Methods: A total of 92 cases of children with respiratory diseases were included in the hospital from February 2013 to March 2015. All children were randomly divided into two groups at random. The control group received intravenous drug therapy and the observation group received oxygen-driven atomization therapy. Comparison of two groups of children’s disease recovery, draw the treatment effect. Results: The mean improvement time of clinical symptoms was (3.82 ± 0.22) d in 46 children in the control group, the mean duration of oxygen therapy was (2.08 ± 0.33) days and the average length of hospital stay was (10.39 ± 1.73) days. The treatment effect was significant 11 cases, effective in 22 cases, ineffective in 13 cases, the total effective rate was 71.74%. The mean improvement time of clinical symptoms in 46 cases in observation group was (2.52 ± 0.35) d, the average duration of oxygen therapy was (1.32 ± 0.23) days, the average length of stay in hospital was (7.64 ± 1.19) days, and the therapeutic effect was markedly improved in 17 cases , Effective in 26 cases, invalid in 3 cases, the total effective rate was 93.48%. The average clinical symptom improvement time, oxygen therapy time, hospitalization time and total effective rate in both groups were compared (P <0.05), the difference was statistically significant. CONCLUSIONS: In the treatment of children with respiratory diseases, the combined effect of ambroxol hydrochloride aerosol treatment is significantly better than that of injection. Worthy of clinical application.