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目的:探讨急性脑梗死与血浆高同型半胱氨酸(Hcy)血症的关系。方法:选取75例急性脑梗死住院患者和45例同期正常的健康体检者进行血浆Hcy、叶酸和维生素B12的测定,并进行比较。结果:急性脑梗死组患者血浆Hcy水平明显升高,叶酸、维生素B12水平明显低于对照组(P<0.05)。结论:急性脑梗死组患者血浆Hcy升高,而叶酸、维生素B12下降,高同型半胱氨酸血症是急性脑梗死的独立危险因素之一。
Objective: To investigate the relationship between acute cerebral infarction and plasma hyperhomocysteinemia. Methods: The plasma levels of Hcy, folic acid and vitamin B12 in 75 hospitalized patients with acute cerebral infarction and 45 normal controls were measured and compared. Results: Plasma Hcy levels in patients with acute cerebral infarction were significantly higher than those in the control group (P <0.05). Conclusion: Plasma Hcy is increased in patients with acute cerebral infarction, while folic acid and vitamin B12 are decreased. Homocysteinemia is an independent risk factor for acute cerebral infarction.