一、引言目前,头孢菌素的结构改造工作是国内外比较重视的研究工作。在头孢菌素的分离提纯中,有人利用重金属分离法,但还没有看到将其视为络合物的专门研究。我们利用过渡金属离子的光、磁性,研究了金属离子铜(Ⅱ)、钴(Ⅱ)、镍(Ⅱ)、铁(Ⅲ)和铬(Ⅲ)与头孢菌素C的作用,对于理解头孢菌素C的生物无机化学性质、发展头孢菌素C的生产都具有一定的意义。 I. Introduction At present, the structural transformation of cephalosporins is a more important research work at home and abroad. In the cephalosporin separation and purification, some people use heavy metal separation method, but have not seen it as a complex of specialized research. We used the light and magnetism of transition metal ions to study the effect of metal ions such as copper (Ⅱ), cobalt (Ⅱ), nickel (Ⅱ), iron (Ⅲ) and chromium (Ⅲ) The bio-inorganic chemical properties of C, the development of cephalosporin C production has a certain significance.