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目的通过研究本院对围手术期抗菌药物实行干预前后的使用情况,探索抗菌药物合理使用方案实施的可行性,提高医院抗菌药物合理使用水平。方法将干预前后反映抗菌药物使用情况的各项指标进行对比研究。结果实施干预后,手术患者的平均住院日、平均住院费均降低,平均抗菌药费、抗菌药物平均使用品种数、平均使用时间显著降低,手术部位的感染率没有明显变化。结论采取综合措施干预后提高了抗菌药物用药的合理性,对促进抗菌药物安全、有效、经济的使用起到了积极的作用。
Objective To study the use of perioperative antibacterials in our hospital before and after the interventions to explore the feasibility of rational use of antimicrobial agents to improve the rational use of antimicrobial drugs in hospitals. Methods Before and after intervention, the indicators reflecting the use of antimicrobial agents were compared. Results After the implementation of the intervention, the average length of stay and the average hospitalization cost of the patients under surgery decreased. The average number of antimicrobial drugs, the average number of antimicrobial drugs used, the average time of use were significantly reduced, and the infection rate of the surgical site did not change significantly. Conclusion The intervention of comprehensive measures to improve the rational use of antimicrobial drugs, to promote the safe, effective and economical use of antimicrobial drugs played a positive role.