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目的探讨经内镜球囊扩张治疗贲门失弛缓症的疗效及食管动力的变化。方法对2001-01—2005-12于中国医科大学附属第一医院就诊的55例贲门失弛缓症患者,在内镜直视下行球囊扩张治疗,并进行症状评分、食管钡餐造影及食管测压检查。结果经内镜球囊扩张后临床症状明显改善(P<0·01);食管钡餐造影食管最大宽度明显减小(P<0·01);LESP及LESRP明显降低(P<0·01),LESRR明显升高(P<0·01),LESRR与LESP高低无关;食管体部均表现为无效低幅收缩,未恢复推进性蠕动波。结论经内镜球囊扩张治疗贲门失弛缓症可明显缓解患者的临床症状,改善食管动力,是一种简单、安全、有效的治疗方法。
Objective To investigate the efficacy and esophageal motility of endocardial balloon dilatation in the treatment of achalasia. Methods A total of 55 patients with achalasia treated at the First Affiliated Hospital of China Medical University from January 2001 to December 2005 were enrolled in this study. They were undergone balloon dilation under endoscopy and their symptoms, esophageal barium meal and esophageal manometry an examination. Results The clinical symptoms were significantly improved by endoscopic balloon dilation (P <0.01). The maximal esophageal barium meal esophageal diameter was significantly reduced (P <0.01), LESP and LESRP were significantly decreased (P <0.01) LESRR was significantly higher (P <0.01), LESRR and LESP had nothing to do; esophageal body showed ineffective low amplitude contraction, did not recover propulsive peristalsis waves. Conclusion Treatment of achalasia with endocardial balloon dilation can relieve the clinical symptoms and improve the esophageal motility. It is a simple, safe and effective treatment.