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1型人类嗜 T淋巴细胞病毒 ( HTLV- 1 )是成人 T淋巴细胞白血病 ( ATL )和 HTLV-1相关的脊髓病 /热带痉挛性截瘫 ( HAM/TSP)的致病因素 ,特异性细胞免疫应答对于消除慢病毒感染非常重要 ,而多肽类细胞毒性 T细胞 ( CTL)表位疫苗可诱发抗病毒的特异性 CTL 应答。作者研究了 HTLV-
Type 1 human T cell lymphotrophic virus (HTLV-1) is a causative agent of myelopathy / tropical spastic paraplegia (HAM / TSP) associated with HTLV-1 and adult T-cell lymphocytic leukemia (ATL). Specific cellular immune responses It is important to eliminate lentiviral infections, whereas peptide-based cytotoxic T-cell (CTL) epitope vaccines elicit antiviral specific CTL responses. The authors studied the HTLV-