非甲非乙型肝炎病人的血清或血浆接种黑猩猩可以成功地产生此型肝炎。经接种的黑猩猩,其肝细胞有两种超微结构的改变:一种在胞浆中可见独特的结构;另一种仅见细胞核的改变,常表现大小为20～27nm的病毒样颗粒的聚集。此两种改变并不同时发生于同一黑猩猩的肝脏中。因临床上某些病人有重复感染非甲非乙型肝炎的现象,有人 Inoculation of chimpanzees with serum or plasma from non-A, non-B hepatitis patients can produce this hepatitis successfully. Inoculated chimpanzees have two ultrastructural changes of their hepatocytes: one has a unique structure visible in the cytoplasm; the other, with only a change in the nucleus, often shows the accumulation of virus-like particles of 20-27 nm in size. These two changes do not occur simultaneously in the same chimpanzee’s liver. Some patients due to clinical infection with non-repeated non-hepatitis B non-hepatitis, some people