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AIM:To study the influence of HBcAg on the expressionof transforming growth factor-beta 1 (TGF-β1) in livertissue of low-grade chronic hepatitis B (CHB) patients.METHODS:The expression of TGF-β1 and HBcAgin liver samples from 93 low-grade CHB patients wasdetected by immunohistochemistry and valuated bysemi-quantitative scoring.RESULTS:In the 93 low-grade CHB patients,HBcAgwas expressed in cell plasma but not in the liver tissue.There was no significant difference between the twogroups.CONCLUSION:The expression of TGF-β1 is not relatedwith HBcAg expressed as plasma type in the tissues oflow-grade CHB patients.
AIM: To study the influence of HBcAg on the expression of transforming growth factor-beta 1 (TGF-β1) in livertissue of low-grade chronic hepatitis B (CHB) patients. METHODS: The expression of TGF-β1 and HBcAgin liver samples from 93 low-grade CHB patients wasdetected by immunohistochemistry andvaluated bysemi-quantitative scoring.RESULTS: In the 93 low-grade CHB patients, HBcAgwas expressed in cell plasma but not in the liver tissue. There was no significant difference between the twins.CONCLUSION: The expression of TGF-β1 is not related with HBcAg expressed as plasma type in the tissues of low-grade CHB patients.