论文部分内容阅读
目的:研究窒息新生儿血清心肌酶水平的变化,并探讨其临床意义。方法:选取2009年5月～2011年5月我院80例新生儿为研究对象,根据新生儿窒息程度,将其分为轻度窒息组(54例)和重度窒息组(26)例,同时,选取同时期30例正常足月新生儿为对照组,对比3组新生儿血清中的CK-MB、CK、LDH、AST以及α-HBDH等多种心肌酶进行检测,观察血清心肌酶水平变化。结果:与对照组新生儿相比,轻度窒息组和重度窒息组新生儿血清中CK-MB、CK、LDH、AST以及α-HBDH水平偏高,对比差异明显,具有统计学意义(P<0.05);重度窒息组新生儿血清中CK-MB、CK、LDH、AST以及α-HBDH水平比轻度窒息组新生儿高,对比差异明显,具有统计学意义(P<0.05)。结论:新生儿血清心肌酶水平可用于监测、治疗新生儿窒息后心肌损害,为早期窒息新生儿治疗提供了依据,值得临床应用。
Objective: To study the changes of serum myocardial enzyme levels in neonates with asphyxia and to explore its clinical significance. Methods: From May 2009 to May 2011, 80 newborns in our hospital were selected as study objects. According to the degree of neonatal asphyxia, they were divided into mild asphyxia group (54 cases) and severe asphyxia group (26 cases) , 30 normal newborn infants in the same period were selected as the control group. CK-MB, CK, LDH, AST, α-HBDH and other myocardial enzymes in 3 neonates were compared. The levels of serum myocardial enzymes . Results: The levels of serum CK-MB, CK, LDH, AST and α-HBDH in neonates with mild asphyxia group and severe asphyxia group were significantly higher than those in the control group, with significant difference (P < 0.05). Serum levels of CK-MB, CK, LDH, AST and α-HBDH in neonates with severe asphyxia group were significantly higher than those in mild asphyxia group (P <0.05). Conclusion: The levels of serum myocardial enzymes in newborns can be used for monitoring and treatment of neonatal asphyxia after myocardial injury, which provides the basis for the treatment of neonatal asphyxia and is worthy of clinical application.