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含药治疗贴膏的研制在国外取得相当的进展,其中透皮吸收的贴膏已逐步取代针、片等剂型,深受用户欢迎,因为它能使药物以恒定的速率直接输入血液,并在敷贴后一旦感觉不适,可立即揭去而消除副反应,保证用药的安全、有效。如东茛菪碱(抗胆碱药)具有镇静和抑制胃酸分泌的作用,对于防治晕车和胃溃疡有良好的疗效,但本品对人的个体敏感性有极大差异,有时常用量亦能引起幻觉、谵妄等毒副作用,服用颇为不便。现制成透皮吸收贴膏,减少了副作用,因而成为热销产品。
Development of drug-containing therapeutic plasters has made considerable progress in foreign countries. Among them, transdermal patches have gradually replaced needles, tablets, and other dosage forms. They are popular among users because they enable drugs to be directly delivered to blood at a constant rate, and After the application, if it feels uncomfortable, it can be immediately removed to eliminate adverse reactions and ensure the safety and effectiveness of the medication. For example, scopolamine (anticholinergic drugs) has a sedative effect and inhibits gastric acid secretion. It has good curative effect on the prevention and cure of motion sickness and gastric ulcers, but this product has a great difference in the individual sensitivity of humans. Sometimes the amount used can also cause hallucinations, It is inconvenient to take such toxic side effects as expectoration. It is now made into a transdermal patch that reduces side effects and becomes a hot product.