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目的 :探讨高血压病患者使用降血压药缬沙坦后对血糖血脂的影响。方法 :选择我院门诊高血压病患者 12 5例 ,治疗组89例 ,给缬沙坦 80晨服 ,对照组 3 6例为不愿接受药物治疗者。治疗前均化验空腹血糖 (FBG)、总胆固醇 (TC)、甘油三酯 (TC)、低密度脂蛋白胆固醇 (LDL -C)高密度脂蛋白胆固醇 (HDL -C) ,每周门诊随访 1次 ,4周后重复上述检查。结果 :缬沙坦治疗组收缩压、舒张压、TC、TG、LDL -C均明显下降 ,P <0 .0 5 ,而FBG、HDL -C无明显变化 ;对照组 4周前后血糖血脂均无明显变化。结论 :高血压病患者用降血压药缬沙坦后 ,不仅血压明显下降 ,TC、TG、LDL -C亦有不同程度下降。
Objective: To investigate the effect of valsartan on blood glucose and blood lipid in hypertensive patients. Methods: A total of 125 outpatients with hypertension were enrolled in this study. 89 patients in the treatment group were given morning service of valsartan 80 and 36 patients in the control group were unwilling to receive medication. Before treatment, fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TC) and low density lipoprotein cholesterol (HDL-C) and high density lipoprotein cholesterol After 4 weeks, repeat the above examination. Results: The values of systolic blood pressure, diastolic blood pressure, TC, TG and LDL-C of valsartan treatment group were significantly decreased, P <0.05, but no significant changes of FBG and HDL-C; obvious change. Conclusion: Hypertension patients with antihypertensive drugs valsartan, not only decreased blood pressure, TC, TG, LDL-C also decreased to varying degrees.