An ethylene diamine tetra acetic acid (EDTA) precursor-based chemical method is reported for preparing single-phase nickel ferrite (NiFe 2 O 4 ) nanopowder. The synthesized powder was characterized by thermogravimetric analysis, differential scanning calorimetric analysis, X-ray diffraction, particle size analysis and scanning electron microscopy. DC electrical resistivity and magnetic property of the syn- thesized NiFe 2 O 4 were measured by using a two-probe method and a vibrating sample magnetometer respectively. The DC resistivity behaviour of the NiFe 2 O 4 nanopowder was correlated with the change of microstructure, during sintering. This EDTA precursor-based method is capable of producing nanos- tructured single-phase NiFe 2 O 4 powder at a comparatively low calcination temperature and offers the potential of a simple and cost-effective route, including the preparation of other ferrite nanoparticles. An ethylene diamine tetra acetic acid (EDTA) precursor-based chemical method is reported for preparing single-phase nickel ferrite (NiFe 2 O 4) nanopowder. The synthesized powder was characterized by thermogravimetric analysis, differential scanning calorimetric analysis, X-ray diffraction, particle size analysis and scanning electron microscopy. DC electrical resistivity and magnetic property of the syn-thesized NiFe 2 O 4 were measured by using a two-probe method and a vibrating sample magnetometer respectively. The DC resistivity behavior of the NiFe 2 O 4 nanopowder This EDTA precursor-based method is capable of producing nanos-tructured single-phase NiFe 2 O 4 powder at a relatively low calcination temperature and offers the potential of a simple and cost-effective route , including the preparation of other ferrite nanoparticles.