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患者男,17岁。右足趾间菜花状增生物1月余。皮肤科情况:右足各趾间见数枚大小不等的菜花状增生物,部分浸渍糜烂。双足趾间皮肤浸渍、糜烂,部分脱屑,双足底皮肤片状脱屑。皮损组织病理示:角化过度,真表皮乳头瘤样增生,表皮颗粒层及棘层上部多量凹空细胞。采用聚合酶链式反应(PCR)检测皮损HPV分型:HPV-58阳性。局部皮肤真菌镜检:阳性。血HIV,TPPA,RPR检查均阴性。诊断:1.趾间尖锐湿疣(高危型);2.足癣。予CO_2激光治疗尖锐湿疣,同时予抗真菌治疗,2周后随访未见新发疣体,足癣皮损基本痊愈。目前仍在随访中。
Patient male, 17 years old. Right foot toe between cauliflower more than 1 month. Dermatology: right foot to see between the number of different size cauliflower accretions, partial immersion erosion. Dip toe between the skin impregnation, erosion, some scaling, bipedal skin flake scaling. Histopathology showed lesions: hyperkeratosis, epidermal papilloma-like hyperplasia, epidermal granular layer and the upper part of the stratum spinosum hollow cells. Polymerase chain reaction (PCR) was used to detect skin lesions HPV type: HPV-58 positive. Topical skin fungus microscopy: positive. Blood HIV, TPPA, RPR tests were negative. Diagnosis: 1. Toe genital warts (high-risk type); 2. Tinea pedis. To CO_2 laser treatment of genital warts, anti-fungal treatment at the same time, no follow-up after 2 weeks of new wart body, tinea pedis skin lesions basically cured. Currently under follow-up.