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本文报告我科治疗嗜酸性淋巴肉芽肿患者16例。在治疗前、后和定期随诊中均做骨髓穿刺检查,同时以外周血象进行对照观察。发现骨髓和血象改变相似,主要表现为成熟嗜酸性粒细胞增高,其阳性率均为75％,只是外周血比骨髓更明显。同一患者两方面均增高者占全组69％,为增高者92％,此可做为该病第三大特征。通过治疗随访观察,发现上述之动态与疗效呈密切平行关系,而这种动态平行变化又可成为此症诊断、疗效评价、预后估计和序贯治疗之客观指标。对早期诊断、正确治疗和提高疗效具有重要指导意义。
This article reports 16 cases of eosinophilic lymphogranuloma in our department. In the treatment before and after regular follow-up are bone marrow biopsy, while peripheral blood as control. Found that bone marrow and blood changes are similar, mainly as mature eosinophils increased, the positive rate was 75%, only the peripheral blood is more obvious than the bone marrow. The same patient increased in both groups accounted for 69% of the whole group, 92% higher, this can be the third major feature of the disease. Through the follow-up of treatment, it was found that the above dynamic and therapeutic effects were closely related to each other. However, this dynamic parallel change may become an objective indicator of the diagnosis, evaluation of curative effect, prognosis and sequential therapy. For early diagnosis, correct treatment and improve the efficacy of an important guiding significance.