This paper studies the electronic transport in an individual helically twisted CdS nanowire rope, on which platinum microleacls are attached by focused-ion beam deposition. The current-voltage (Ⅰ - Ⅴ ) characteristics are nonlinear from 300 down to 60 K. Some step-like structures in the Ⅰ - Ⅴ curves and oscillation peaks in the differential conductance (dⅠ/dⅤ - Ⅴ) curves have been observed even at room temperature. It proposes that the observed behaviour can be attributed to Coulomb-blockade transport in the one-dimensional CdS nanowires with diameters of 6-10 nm.