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目的探讨阿维菌素(AVM)对生产工人的血化清生指标的影响,为今后职业卫生相关问题的研究积累资料和提供依据。方法以53名阿维菌素生产人员和29名非作业人员为研究对象,采集空腹静脉血,分别测定血清丙氨酸氨基转移酶(ALT)等6项生化指标,同时测定生产环境阿维菌素浓度。结果接触组白蛋白(ALB)均值低于对照组,差异有统计学意义(P<0.05)。结论在AVM浓度为61.35~154.64 ug/m3的环境中,平均暴露2~3年,对血清生化指标有轻微影响,可见白蛋白降低。
Objective To investigate the effect of avermectin (AVM) on the index of bloodization and clearance of production workers and to accumulate data and provide evidences for the study of occupational health related problems in the future. Methods Fifty-three abamectin producers and 29 non-working staff were enrolled in this study. Fasting venous blood was collected and serum biochemical indexes such as alanine aminotransferase (ALT) were measured. Avermectin Sufficient concentration. Results The average albumin (ALB) in exposure group was lower than that in control group (P <0.05). Conclusions In the environment with AVM concentration of 61.35-154.64 ug / m3, the mean exposure time is 2-3 years, which has a slight effect on serum biochemical indexes, and the albumin is reduced.