经前期综合征(premenstrual syndrome,PMS)是指月经来潮前周期性出现影响妇女日常生活和工作的躯体、精神及行为的一组症候群,发病率较高,目前病因尚不明确。其治疗主要包括非药物治疗和药物治疗。口服避孕药(oral contraceptive,OCP)由于其特殊性质近来被考虑应用于治疗PMS。第三代孕激素屈螺酮的出现让OCP治疗PMS出现曙光,研究表明含屈螺酮的OCP可以显著改善PMS症状,包括躯体、精神、行为症状,其效果优于其他OCP,且缩短OCP无激素间隔可能效果更好。 Premenstrual syndrome (PMS) refers to a group of symptoms that occur periodically before menstruation and affect the physical, mental and behavioral aspects of women’s daily life and work. The incidence is high and the cause is not yet clear. The treatment mainly includes non-drug treatment and drug treatment. Oral contraceptives (oral contraceptives, OCP) because of its special nature has recently been considered for the treatment of PMS. The emergence of the third generation of progesterone drospirenone for OCP treatment of PMS appear dawn, studies have shown that drospirenone OCP can significantly improve symptoms of PMS, including physical, mental, behavioral symptoms, the effect is better than other OCP, and shorten the OCP without hormone Interval may be better.