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目的探讨早发型重度子痫前期的预期治疗与围生结局的相关性。方法选取2010年12月至2011年12月早发型重度子痫前期产妇93例,以产妇孕周差异为依据将其分为A、B、C三组,每组31例,A组孕28~29周,B组孕30~31周,C组孕32~33周,对三组产妇的预期治疗时间、孕龄延长、新生儿体质量增加及围生结局进行对比。结果 B组产妇的预期治疗时间、孕龄延长、新生儿体质量增加均明显高于A、C两组(P<0.05),C组产妇的预期治疗时间明显高于A组(P<0.05),但两组产妇的孕龄延长、新生儿体质量增加比较差异无统计学意义(P>0.05);随着孕周的增加,新生儿病死率及窒息率均有所下降。结论给予早发型重度子痫前期患者预期治疗能有效改善产妇新生儿的围生结局,临床效果显著,值得临床推广。
Objective To investigate the relationship between the expected treatment of early-onset severe preeclampsia and the outcome of perinatal period. Methods Ninety-three pregnant women with early-onset severe preeclampsia from December 2010 to December 2011 were divided into three groups A, B and C on the basis of gestational age differences among the 31 women in each group, 29 weeks, group B pregnant 30-31 weeks, group C pregnant 32-33 weeks, expected treatment time of the three groups of maternal, gestational age, newborns increased body mass and perinatal outcome were compared. Results The expected treatment time, prolonged gestational age and body weight of newborns in group B were significantly higher than those in groups A and C (P <0.05). The expectant treatment time in group C was significantly higher than that in group A (P <0.05) , But there was no significant difference in body weight of newborns between the two groups (P> 0.05). With the increase of gestational age, neonatal mortality and asphyxia decreased. Conclusions The expected treatment for patients with early-onset severe preeclampsia can effectively improve the perinatal outcome of neonates with maternal morbidity. The clinical effect is significant and is worthy of clinical promotion.