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对虾白黑斑病是养殖中国对虾的常见病，曾被怀疑是细菌性疾病。本试验通过对病虾肝胰腺、血液和病灶组织的细菌分离，对正常虾用自黑斑病虾投喂感染，与病虾共栖感染以及用分离于病虾的细菌注射感染等一系列试验发现：细菌或其它生物性病原与对虾白黑斑病并无直接关系。通过对病虾的酚氧化酶活力测定．血细胞的观察和流行病学研究．分析认为该病是由于对虾长期营养不良在应激状态下所引发的一种生理性疾病。腹部每节两侧基部和尾肢等部位出现的病灶──白班或黑斑是在对虾处于应激状态下，酚氧化酶诱导相关基质山酚到醌最终产生黑色素形成的。此外还讨论了相关基质的来源以及与对虾应激反应有关的几项因素。
White spot black shrimp is a common disease of shrimp farming in China. It was suspected to be a bacterial disease. In this experiment, a series of experiments were carried out on the bacterial isolation of hepatopancreas, blood and lesion tissue of diseased shrimp by feeding the normal shrimp with black spot shrimp, co-infecting the diseased shrimp and injecting the bacteria isolated from diseased shrimp Bacteria or other biological pathogens are not directly related to white spot disease of shrimp. Through the disease shrimp phenoloxidase activity determination. Blood cell observation and epidemiological studies. Analysis that the disease is due to shrimp long-term malnutrition in the stress caused by a physiological disease. Lesions in the basal and caudal limbs on both sides of the abdomen ─ ─ white or dark spots in the stress state of shrimp, phenoloxidase-induced substrate-derived phenols to quinone eventually produce melanin formation. The sources of the relevant matrices and several factors related to the stress response to shrimp are also discussed.