目的：探讨我市农村出生缺陷的临床特征，为临床制订干预措施提供科学依据。方法：对我市农村出生缺陷的发生率和特征进行临床分析，与城市出生缺陷进行比较。结果：我市农村出生缺陷发生率为73.51/万，城乡出生缺陷发生率有显著差异，农村出生缺陷发生率比城市高近一倍，（P均＜0.005），农村出生缺陷前三位依次为消化系统畸形、四肢畸形和神经系统畸形，分别占出生缺陷的28.39%、24.15%和11.86%。结论：我市农村出生缺陷发生率还处于较高水平，而且神经系统出生缺陷比较突出，主要原因是农村育龄妇女对口服叶酸预防出生缺陷等措施不理解、不接受，思想认识还未真正提高；基层围产保健水平低。我市农村人口占80%以上，因此，在制定出生缺陷干预对策时，应将重点放在影响人力资源与人民生活质量的病种和农村上。“,”Goal To investigate the clinical characteristics of birth defects in our city, and to provide scientific basis for clinical intervention. Methods the incidence and characteristics of birth defects in rural areas were analyzed, and compared with the urban birth defects. Finally The city rural birth defect rate 73.51/, urban and rural birth defect rate has the remarkable difference, rural incidence of birth defects rate nearly one times higher than that of urban, respectively (P<0.005). The rural birth defects in the former three followed by digestive system malformations, limb deformities and nervous system malformation, respectively, accounting for birth defects of 28.39%and 24.15%and 11.86%. Discussion our city rural birth defects incidence is still at a higher level and nervous system of birth defects is more outstanding, main reason is rural women of childbearing age oral folic acid to prevent birth defects and other measures do not understand, do not accept and ideas have not really improve;primary Wai care level is low. Our city rural population accounts for more than 80%, therefore, in the development of birth defects intervention measures should be focused on the impact of human resources and the quality of life of the people and the rural areas.