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目的分析急性脑梗死患者的血栓弹力图指标,以指导与监测阿司匹林治疗过程与疗效。方法资料随机选取2013年1月—2014年1月本院诊治的急性脑梗死患者98例,分析入院时与治疗后的TEG指标,探讨不同神经功能缺损程度与TEG指标的相关性。结果与入院时比较,患者治疗后的R时间与K时间均明显延长,α角、MA值、G值显著减小,CI值明显降低,均有统计学意义(P<0.05);神经功能缺损程度与R时间、K时间呈负正相关性,与α角、MA值、G值、CI值呈负相关性。结论急性脑梗死患者凝血功能多存在高凝倾向,血栓弹力图对于监测阿司匹林治疗过程与效果,评估神经功能缺损程度具有应用价值。
Objective To analyze the index of thromboelastography in patients with acute cerebral infarction to guide and monitor the course and effect of aspirin treatment. METHODS: A total of 98 acute cerebral infarction patients diagnosed and treated in our hospital from January 2013 to January 2014 were randomly selected. The TEG indexes after admission and after treatment were analyzed to explore the correlation between different neurological deficits and TEG index. Results Compared with those at admission, the R and K time of patients were significantly prolonged after treatment. The α, MA and G values were significantly decreased and the CI values were significantly decreased (all P <0.05). The neurological deficits There was a negative correlation between the degree and R time and K time, and negative correlation with α angle, MA value, G value and CI value. Conclusion There is a tendency of hypercoagulation in patients with acute cerebral infarction. The thrombus elasticity map is of value in monitoring the course and effect of aspirin treatment and evaluating the degree of neurological deficit.