对１１名单甲脒包装女工作为期４个月的健康效应的前瞻定群调研。下午班后双手单甲脒污染量为６．３８ｍｇ／ｃｍ２，尿中总浓度为０．４１４ｍｇ／Ｌ接触前为０．０８１ｍｇ／Ｌ；显著表现为头昏、嗜睡、乏力、皮疹、血压下降、心电图异常及尿中儿茶酚胺代谢产物ＶＭＡ减少。累计接触水平与症状体征积分、血压降幅及尿ＶＭＡ浓度间都存在接触－效应关系，提示脒类农药中毒的关键是心血管损害，系通过中枢儿茶酚胺α２受体的激动和对心肌直接损害所致，此为防治脒类农药中毒提供新的理论依据 A prospective cohort study of the health effects of 11 single formamidine women in packaging for a 4-month period. Afternoon classes after single-handed carboxamidine pollution 6.38mg / cm2, the total urinary concentration of 0.414mg / L before the contact was 0.081mg / L; significant dizziness, lethargy, fatigue, rash, blood pressure, Electrocardiogram abnormalities and urinary catecholamine metabolites VMA decreased. Cumulative exposure levels and symptoms and signs score, blood pressure drop and urine VMA concentrations are between the contact-effect relationship, suggesting that amidine pesticide poisoning is the key to cardiovascular damage, through the central catecholamine α2 receptor agonist and myocardial damage caused by direct This provides a new theoretical basis for the control of amidine pesticide poisoning