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新药心脑健系由茶叶中提出的有效物质,经动物实验证明,具有抗凝、促进纤溶,防止血小板粘附,抑制主动脉平滑肌细胞生长,以及防止家兔实验性动脉粥样硬化等的作用。毒性试验表明,本品安全性较大小鼠每天腹腔注射93-165mg/kg连续30d,未发现毒性反应。经浙江医科大学附属第二医院等单位临床验证,对214例心血管病伴高纤维蛋白原症患者,以每天125mg、250mg口服,60d为1疗程。治疗后其中174例血浆纤维蛋白原下降>20mg,下降幅度为20-249mg％:付效率为81.3％,显效率35％,除个别病例有胃部不适、胃纳减退,大便次数增多外,均未见有其它明显不良反应。
Cardiac brain health of the new drug proposed by the effective substances in tea, animal experiments show that with anticoagulant, fibrinolysis, to prevent platelet adhesion, inhibit the growth of aortic smooth muscle cells, and prevent rabbit experimental atherosclerosis effect. Toxicity tests showed that the safety of this product in mice daily intraperitoneal injection of 93-165mg / kg for 30d, no toxic reaction was found. Second Affiliated Hospital of Zhejiang Medical University and other units of clinical validation, 214 cases of cardiovascular disease with high fibroin in patients with daily 125mg, 250mg orally, 60d for a course of treatment. After treatment, 174 cases of plasma fibrinogen decreased> 20mg, a decrease of 20-249mg%: pay efficiency was 81.3%, markedly effective rate of 35%, except for a few cases of stomach discomfort, decreased appetite, stool frequency, both There are no other obvious adverse reactions.