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目的 :探讨用自体腹水浓缩回输腹腔技术治疗大量感染性顽固性腹水的安全性及疗效 ,并对影响疗效的因素进行分析。方法 :应用HAUF -2型腹水超滤机及YT -70SPAN聚丙烯睛中空纤维血液滤过器 ,对 3 5例伴有大量感染性顽固性腹水的肝硬化患者进行自体腹水浓缩后回输腹腔治疗。并对影响疗效的因素进行单因素及回归分析。结果 :经此法治疗后患者体重下降 ( 4 84± 1 42 )kg( P <0 0 0 0 1) ,腹围下降 ( 8 3 9± 3 12 )cm (P <0 0 0 0 1) ,尿量增多 ( 2 95 49± 10 2 1 13 4)ml/ 2 4h(P <0 0 5 )。共放腹水2 5 60 0 0ml ,平均 ( 5 0 19 61± 15 2 6 5 7)ml,回输浓缩液共 2 0 75 0ml ,平均 ( 4 0 6 86± 2 88 10 )ml。总有效率为 48 67% ,未见明显副作用。Child -pugh分级是唯一影响疗效的因素 ,既Child -pughC级疗效差。结论 :自体腹水浓缩回输腹腔技术治疗大量感染性腹水是安全、有效的。
Objective: To explore the safety and curative effect of using ascites concentrated transfusion abdominal cavity technique to treat a large number of infectious refractory ascites, and to analyze the factors influencing curative effect. Methods: HAUF-2 ascites ultrafilter and YT-70SPAN polypropylene hollow fiber hemofilter were used to treat 35 cases of liver cirrhosis complicated with ascitic fluid infection. . The factors affecting the efficacy of single factor and regression analysis. Results: After treatment, the body weight of the patients decreased (84 ± 1 42) kg (P 0 01 0), the abdominal circumference decreased (89 0 3 12) cm (P 0 01 0) Urinary output increased (952 ± 10 2 1 13 4) ml / 2 4h (P <0 05). A total of 25 600 mL of ascites were delivered, with an average of (50 19 61 ± 15 2 6 5 7) ml, and a total of 20 75 0 ml of transfused concentrate, with an average of (406 86 ± 2 88 10) ml. The total effective rate was 48 67%, no obvious side effects. Child-pugh classification is the only factor that affects the efficacy of both Child-pughC grade poor efficacy. CONCLUSION: It is safe and effective to treat ascitic fluid with autologous ascites by transabdominal injection.