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１趋化因子及其受体的生物学特性１．１趋化因子家族 趋化因子是一个涉及到淋巴细胞游动和活化的结构相似的小分子超家族，其分子量大多在８－１０ＫＤａ。根据其前端４个保守的半胱氨酸残基的空间位置不同，可分为４个亚类［１～３］：第一大类是ＣＣ趋化因子，其前端２个半胱
1 biological characteristics of chemokines and their receptors 1.1 Chemokine family Chemokines is a small molecule superfamily of structurally similar lymphocyte motility and activation, most of its molecular weight in the 8-10KDa. According to their front-end four conserved cysteine residues in different spatial positions, can be divided into four sub-categories [1-3]: The first major category is CC chemokines, the front two cysteines