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顺氯氨铂是(Cis-DDP)阻碍DNP合成的抗癌药物,对睾丸肿瘤、卵巢肿瘤显示特别强的效果,且作为对各种抗癌药反应率非常低的肺非小细胞癌的有效药物正被注目。但是,由于Cis-DDP会引起显著的肾损伤。因此不能长期大量投药。多数情况不能完全治癒。一般认为如果能迅速减轻对实体癌呈卓越效果的本抗癌药的副作用的话,则可大大提高其治疗效果。中药本身所具有的增强免疫作用、抗肿瘤效果、增强抗癌药效果及减轻副作用。因此,本文以中药减轻抗癌药副作用为目的,用小鼠就各种中药对Cis-DDP毒性的效果进行了探讨。
Cis-chlorodichloroplatinum (CiS-DDP) is an anti-cancer drug that blocks DNP synthesis and shows particularly strong effects on testicular and ovarian tumors, and is effective as a non-small cell lung cancer with a very low response rate to various anticancer drugs. Drugs are attracting attention. However, because of Cis-DDP can cause significant kidney damage. Therefore, it cannot be administered in large quantities for a long time. In most cases it cannot be completely cured. It is generally believed that if the side effect of the present anticancer drug which has a remarkable effect on solid cancer can be quickly reduced, the therapeutic effect thereof can be greatly improved. The traditional Chinese medicine itself has enhanced immunity, anti-tumor effects, enhanced anti-cancer drug effects, and reduced side effects. Therefore, the purpose of this article is to reduce the side effects of anti-cancer drugs with traditional Chinese medicine. The effect of various Chinese herbs on the toxicity of Cis-DDP was investigated in mice.