论文部分内容阅读
心肌梗塞后的梗塞扩张引起早期左室扩大及几何形状改变。为阐明远期心室容积增加的成因,52例第一次患急性前壁心肌梗塞患者,病后3周及1年后经过定量左心室造影术检查,测量比较①左室舒张期周长及变化;②收缩与非收缩段长度及变化;③左室几何形状变化。心室整体几何形态用球积指数(心室造影术求得的容积/同周长的圆球体积)表示,局部形态以测量心内膜曲率评价。首次造影后随机,双盲,分安慰剂组及卡托普利治疗组治疗观察一年。结果:梗塞后3周时左室收缩末期容积(ESV)和舒张末期容积(EDV)的明显增大伴左室舒张末期周长及球积指数增加。一年后ESV稳定不变,EDV进一步扩大(从230±42ml到244±55ml,P=
Infarct expansion after myocardial infarction causes early left ventricular enlargement and geometry changes. In order to elucidate the cause of long-term ventricular volume increase, 52 patients with acute anterior myocardial infarction were examined by quantitative left ventricular angiography at 3 weeks and 1 year after the first episode. The left ventricular diastolic phase ; ② systolic and non-systolic length and changes; ③ left ventricular geometric changes. The overall geometry of the ventricle is expressed as the volume index (volume determined by ventriculography / volume of the same circumference), and the local morphology is evaluated as the measurement of endocardial curvature. After the first angiography randomized, double-blind, sub-placebo and captopril treatment group was observed for one year. Results: The left ventricular end-systolic volume (ESV) and end-diastolic volume (EDV) increased significantly at 3 weeks after infarction with the increase of left ventricular end-diastolic volume and volume index. One year later ESV remained unchanged and EDV was further expanded (from 230 ± 42 ml to 244 ± 55 ml, P =