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自从一九七二年,Magnius α Espmark报告了与乙型肝炎病毒有关的e抗元和e抗体系统以来,至今有许多关于基础和临床的问题已研究清楚。日本村上等发现的X抗元,已明确与Magnius等的e抗元相同。作为比欧美各国HBsAg携带率高的日本,对新发现的e抗元和e抗体系统的探索更为热心,尽管如此,对e抗元的本质尚没有一致的见解,至今还是不太了解。 关于临床的意义,Magnius最初报告中记载,肝炎病毒传染性高的人工透析患者血清中,e抗元阳性率高,传染性低的无症状
Since 1972, Magnius α Espmark reported hepatitis E virus-related anti-e and e antibody systems, so far there are many basic and clinical issues have been studied. Xun Yuan discovered by Murakami in Japan has been clearly identified with Magnius et al. Japan, which has a higher carrying rate of HBsAg than its counterparts in Europe and the United States, is even more enthusiastic about the discovery of newly discovered anti-e and e-antibody systems. However, there is still no consensus on the nature of anti-e antigen and so far it is still not well understood. Regarding clinical implications, Magnius’s initial report chronicled the high prevalence and low infectivity of ascitic antigens in sera of patients with hepatitis-virus-infected dialysis