论文部分内容阅读
目的 探讨重症肌无力胸腺切除术后影响远期生存的因素。方法 采用胸腺切除术治疗 170例重症肌无力患者 ,其中 12 4例术后获得超过 4 0个月的远期随访 ,运用COX回归模型分析可能影响远期预后生存的有关因素 ,包括胸腺的各病理类型、性别、年龄、病程、术前临床Osserman分型和治疗。结果 本项研究表明 ,胸腺的不同病理类型是影响胸腺切除术后远期生存的唯一重要因素 ,术后远期生存率有明显差异 ,表现为胸腺增生 >良性胸腺瘤 >胸腺萎缩 >恶性胸腺瘤 (P <0 0 5 )。结论 胸腺的不同病理类型是影响重症肌无力胸腺切除术远期生存的重要因素。
Objective To investigate the factors that affect the long-term survival after thymectomy for myasthenia gravis. Methods A total of 170 patients with myasthenia gravis underwent thymus resection. Among them, 124 patients were followed up for more than 40 months. COX regression analysis was used to analyze the factors that may affect long-term prognosis, including the pathological changes of thymus Type, gender, age, duration of disease, preoperative Osserman classification and treatment. Results The study showed that different pathological types of the thymus are the only important factors affecting the long-term survival after thymectomy. The postoperative long-term survival rate was significantly different, showing thymus hyperplasia> benign thymoma> thymus atrophy> malignant thymoma (P <0 05). Conclusion Different pathological types of the thymus are important factors affecting the long-term survival of thymectomy for myasthenia gravis.