论文部分内容阅读
观察２４例心脏瓣膜替换术后急性心功能不全患者，静脉注射氨力农对血液动力学的影响。结果显示，注射后５ｍｉｎ心脏指数（ＣＩ）、每搏指数（ＳＩ）、左心作功指数（ＬＣＷＩ）和左心每搏作功指数（ＬＶＳＷＩ）均显著增高（Ｐ＜０．０５）；肺动脉楔压显著降低（Ｐ＜０．０５）；ＣＩ、ＳＩ、ＬＣＷＩ和ＬＶＳＷＩ于注射后６０ｍｉｎ增加最为明显（Ｐ＜０．０１），随后均维持在较稳定的水平；注射后３０ｍｉｎ体循环阻力指数、肺循环阻力指数和右房压亦显著降低（Ｐ＜０．０５）；心率、平均动脉压、平均肺动脉压和心率收缩压乘积，在用药期间均无显著改变；右心作功指数和右心每搏作功指数虽有升高的趋势，但无统计学意义。提示氨力农静脉注射后继以静脉滴注，在短时间内能有效地改善瓣膜替换术后急性心功能不全患者的血液动力学，而不增加心肌耗氧量。
To observe the effects of intravenous injection of amrinone on hemodynamics in 24 patients with acute cardiac insufficiency after heart valve replacement. The results showed that the CI, SI, LCWI and LVSWI were all significantly increased 5 min after injection (P <0.05). The pulmonary artery (P <0.05). The CI, SI, LCWI and LVSWI increased most significantly at 60 min after injection (P <0.01), and then maintained at a relatively stable level. After 30 min of injection, the values of systemic resistance index, Pulmonary resistance index and right atrial pressure were significantly lower (P <0.05); heart rate, mean arterial pressure, mean pulmonary artery pressure and heart rate systolic pressure product, no significant changes during the medication; right heart work index and right heart each Although the stroke power index increased trend, but no statistical significance. It is suggested that intravenous infusion of amrinone followed by intravenous infusion can effectively improve the hemodynamics of patients with acute cardiac insufficiency after valvular replacement in a short time without increasing myocardial oxygen consumption.