迄今已有大量的报道,证明干扰素能抑制离体细胞的增殖。干扰素的这种直接生长抑制作用可以有种种的解释。有认为干扰素具有细胞生长抑制作用(cytostatic);也有人解释认为干扰素具有分化诱导作用(differentiation induction)。正因有上述作用,干扰素可用作为抗肿瘤药物。虽然也有不少研究者强调干扰素具有免疫活性,但本研究结果更支持干扰素的直接生长抑制作用。 A large number of reports have so far demonstrated that interferon can inhibit the proliferation of ex vivo cells. There are various explanations for this direct growth inhibitory effect of interferon. It is believed that interferons have a cytostatic effect; it has also been explained that interferons have a differentiation induction. Because of these effects, interferon can be used as an anti-tumor drug. Although many researchers have emphasized that interferon has immunological activity, the results of this study support the direct growth inhibition of interferon.