作者报告3例急性坏死性脊髓病合并有严重的活动性肺结核。并提醒注意这种合并可能和脱髓鞘疾病的病原有关。例143岁男性,在用多种抗结核药物(包括每天900毫克异烟肼)治疗反复复发的肺结核时出现了两侧球后视神经炎。两天后乃停用所有抗结核药物。39天后发生以背疼为先兆、发展迅速的进行性脊髓病。脑脊液中嗜中性细胞增多、蛋白增高、糖低下。细菌学检查阴性。尸检发现双肺广泛性结核、脑脊 The authors report 3 cases of acute necrotizing spinal cord disease with severe active tuberculosis. And cautions that this combination may be related to the pathogen of demyelinating disease. A 143 year old male had bilateral posterior optic neuritis on repeated recurrent tuberculosis with various antituberculosis drugs, including 900 mg of isoniazid per day. Two days later, all anti-tuberculosis drugs were discontinued. 39 days after the occurrence of back pain as a precursor to the rapid development of progressive myelopathy. Cerebrospinal fluid increased neutrophils, increased protein, low sugar. Bacteriological examination negative. Autopsy found extensive lung tuberculosis, cerebrospinal