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目的探究葵花护肝片联合琥珀酸美托洛尔治疗高血压的临床效果。方法 124例高血压患者随机分为观察组和对照组,每组62例。对照组给予琥珀酸美托洛尔治疗,观察组在对照组基础上加用葵花护肝片治疗。观察两组临床疗效。结果治疗12周后,观察组血压下降情况为:收缩压(33.37±16.13)mm Hg(1 mm Hg=0.133 k Pa),舒张压(16.20±8.61)mm Hg。对照组血压下降情况为:收缩压(30.45±12.88)mm Hg;舒张压(11.59±10.26)mm Hg,两组比较差异具有统计学意义(P<0.05)。两组肝损伤情况比较差异具有统计学意义(P<0.01)。结论葵花护肝片联合琥珀酸美托洛尔治疗高血压效果显著,可在临床推广。
Objective To investigate the clinical effect of sunflower liver tablet combined with metoprolol succinate in the treatment of hypertension. Methods 124 cases of hypertension were randomly divided into observation group and control group, with 62 cases in each group. The control group was treated with Metoprolol succinate. The observation group was treated with sunflower liver tablet on the basis of the control group. The clinical effects of two groups were observed. Results After 12 weeks of treatment, the decrease of blood pressure in observation group was: systolic pressure (33.37 ± 16.13) mm Hg (1 mm Hg = 0.133 kPa) and diastolic pressure (16.20 ± 8.61) mm Hg. The decrease of blood pressure in the control group was: systolic blood pressure (30.45 ± 12.88) mm Hg and diastolic blood pressure (11.59 ± 10.26) mm Hg, the difference between the two groups was statistically significant (P <0.05). The difference of liver injury between the two groups was statistically significant (P <0.01). Conclusion Sunflower Liver tablets combined with Metoprolol succinate for the treatment of hypertension has a significant effect, which can be clinically promoted.