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目的了解河北省卢龙县流行性出血热(EHF)的流行病学特征和流行因素,为预防和控制该病提供科学依据。方法采用流行病学调查的方法对病人进行调查,采用间接免疫荧光技术(IFAT)检测EHF抗原的方法进行鼠带毒情况的监测,采用夜夹法进行鼠密度调查。结果 EHF的流行特征:EHF各月份均有病例发生,其中以3—5月为发病高峰期;发病年龄2~76岁,其中以30~49岁年龄组为多;自然感染率为6%;鼠密度为3.32%;鼠带毒率为10.55%。结论开展全民灭鼠活动和疫苗接种是预防和控制该病的有效措施。
Objective To understand the epidemiological and epidemic factors of epidemic hemorrhagic fever (EHF) in Lulong County of Hebei Province and provide a scientific basis for the prevention and control of the disease. Methods The epidemiological investigation method was used to investigate the patients. The indirect immunofluorescence assay (IFAT) was used to monitor the EHF antigen in mice. The night clip method was used to investigate the density of rats. Results The epidemiological characteristics of EHF: EHF cases occurred in each month, of which 3 to 5 months for the peak incidence; the age of onset of 2 to 76 years, of which 30 to 49 age group as much; natural infection rate of 6%; Rat density was 3.32%; rat poisoning rate was 10.55%. Conclusion It is an effective measure to prevent and control the disease by carrying out all rodent control activities and vaccination.